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[ 290OPCHNMRU19 ] UE (*)Interpretation of NMR Spectra and Structure Elucidation of Organic Molecules
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(*) Leider ist diese Information in Deutsch nicht verfügbar.
Workload Ausbildungslevel Studienfachbereich VerantwortlicheR Semesterstunden Anbietende Uni
1,5 ECTS B2 - Bachelor 2. Jahr Chemie Mario Waser 1 SSt Johannes Kepler Universität Linz
Detailinformationen
Quellcurriculum Bachelorstudium Chemistry and Chemical Technology 2025W
Lernergebnisse
Kompetenzen
(*)• Theoretical understanding: Students would be able to explain fundamental aspects of NMR spectroscopy, including basic theory, principles, and concepts. • Data analysis: They would become proficient in interpreting complex NMR spectra, including 1D and 2D data • Structural elucidation: Students would be able to analyse conformational, structural, and functional problems within organic compound classes using NMR methods • Problem-solving: They would develop the ability to predict which NMR experiments to use for solving specific structural or functional problems • Communication: They would be able to present NMR-based structural or functional analyses of organic compounds both in written and oral formats
Fertigkeiten Kenntnisse
(*)More specifically, upon completion of the course they will be able to: • understand basic NMR principles: Students learn the fundamental concepts of nuclear magnetic resonance, including spin properties, magnetic field interactions, and resonance phenomena. (k1,k2,k3) • signal identification and analysis: The course teaches how to identify and analyse different types of signals, including chemical shifts, multiplicities, and coupling constants. (k1,k2,k3,k4) • molecular structure interpretation: Students practice deducing molecular structures based on NMR data, including identifying functional groups and molecular fragments. (k1,k2,k3,k4,k5) • spectrum reading and integration: The course covers how to read and interpret NMR spectra, including peak integration to determine the number of equivalent nuclei. (k1,k2,k3,k4) • understanding the effects of chemical environment: Students learn how different chemical environments affect NMR signals, including shielding and de-shielding effects. (k1,k2,k3,k4) • recognizing common patterns: The course helps students to identify common spectral patterns associated with specific molecular features. (k1,k2,k3,k4) • correlating spectral data: Students practice correlating data from different types of NMR experiments (e.g., 1H and 13C NMR) to build a comprehensive understanding of molecular structure. (k1,k2,k3,k4) • problem-solving and critical thinking: The course develops analytical skills to solve complex spectral interpretation problems. (k1,k2,k3,k4) • Understanding limitations: The course covers the limitations of basic NMR techniques and introduce advanced NMR methods for more complex structural analysis. (k1,k2,k3,k4,k5) (*)Underlying concepts and mechanistic details of: • Basic NMR principles: Understanding the fundamental concepts of nuclear magnetic resonance, including spin properties, magnetic field interactions, and resonance phenomena • Chemical shift analysis: Learning about chemical shifts, factors influencing them, and their relationship to molecular structure • Spin-spin coupling: Comprehending the principles of spin-spin coupling and analysing first-order coupling patterns • Spectrum interpretation: Developing skills to analyse and interpret 1D and 2D NMR spectra, including peak identification, integration, and correlation of spectral data. • Experimental techniques: Familiarizing with various NMR experiments, including 1D and 2D techniques, and learning how to choose appropriate experiments for specific structural analyses • Structural elucidation: Applying NMR data to determine molecular structures and identify unknown compounds • Advanced NMR methods: Introduction to more complex NMR techniques and their applications in organic chemistry • Limitations and problem-solving: Recognizing the limitations of NMR spectroscopy and developing critical thinking skills to address complex spectral interpretation problems
Beurteilungskriterien (*)Performance in written homework (spectral interpretation and assignment tasks and structure elucidations)
Lehrmethoden (*)Presentations and hands-on exercises
Abhaltungssprache Englisch
Literatur (*)
  • High-Resolution NMR Techniques in Organic Chemistry, TIMOTHY D W CLARIDGE, Chemistry Research Laboratory, Department of Chemistry, University of Oxford
  • NMR — From Spectra to Structures - An Experimental Approach; Mitchell, Terence N., Costisella, Burkhard
  • NMR Spectroscopy: Basic Principles, Concepts, and Applications in Chemistry; Harald Günther
Lehrinhalte wechselnd? Nein
Sonstige Informationen (*)It is recommended to take this course in parallel to the Laboratory Course of Preparative Organic Chemistry for Biological Chemistry 1.
Frühere Varianten Decken ebenfalls die Anforderungen des Curriculums ab (von - bis)
290OPCHSP1U18: UE Exercises in Spectroscopy and Structure Elucidation I (2018W-2019S)
Präsenzlehrveranstaltung
Teilungsziffer 25
Zuteilungsverfahren Direktzuteilung