| Detailed information |
| Pre-requisites |
(*)Zulassung zum Doktoratsstudium Medical Sciences, Naturwissenschaften bzw. Technischen Wissenschaften
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| Original study plan |
Doctoral programme Medical Sciences 2025W |
| Learning Outcomes |
Competences |
| Students develop a comprehensive understanding of biological membranes in excitable cells particularly of the musculoskeletal and nervous system. This includes how these cells operate within their environment and local networks. The structure and physiology of ion channels, receptors and membrane transporters and the core electrical properties of biological membranes will be introduced. The lecture also covers the basics of molecular components of excitable membranes, their interactions with the extracellular space and neuronal myelin sheaths also in the context of human disease.
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| Skills |
Knowledge |
| Gaining fundamental insight into biological membrane properties, the proteins associated with cellular excitation and their interaction with the extracellular space.
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- Basic concepts of biological membranes with a focus on excitable cells in the musculoskeletal and nervous system
- Basic concepts of structure – function relationships regarding ion channels, membrane transporters and receptors
- Basic understanding of how aberrant membrane composition and excitation underly human disease mechanisms
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| Criteria for evaluation |
Attendance of at least 75 %.
Active participation during the discussion.
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| Methods |
Lectures by instructor(s) and discussions.
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| Language |
English |
| Study material |
Alberts et al., Molecular Biology of the Cell, 8th edition, WW Norton & Co, 2024
Selected publications provided by the lecturer and autodidactic search of PubMed and other sources.
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| Changing subject? |
No |
