(*) Leider ist diese Information in Deutsch nicht verfügbar.
Workload
Ausbildungslevel
Studienfachbereich
VerantwortlicheR
Semesterstunden
Anbietende Uni
3 ECTS
R - Doktorat / PhD
Humanmedizin
Yong Yu
2 SSt
Johannes Kepler Universität Linz
Detailinformationen
Anmeldevoraussetzungen
Zulassung zum Doktoratsstudium Medical Sciences
Quellcurriculum
Doktoratsstudium Medical Sciences 2025W
Lernergebnisse
Kompetenzen
(*)Students understand the role and function of extrachromosomal DNAs (ecDNAs) and their connection to oncogene amplification in cancer. They can perform advanced molecular techniques as well as imaging through microscopy techniques and molecular staining techniques and analysing and interpretation of results.
Fertigkeiten
Kenntnisse
(*)
Performing premature chromosome condensation (PCC) to produce metaphase chromosomes.
Staining and visualizing ecDNAs.
Using fluorescence in situ hybridization (FISH) to detect amplified oncogenes on ecDNA in human cancer cells.
Preparing slides and using a fluorescence microscope to observe experimental results.
Analyzing and interpreting experimental data related to ecDNA and oncogene amplification.
Describe experimental procedures and results.
(*)
The biological function and role of ecDNA in cancer.
Mechanisms of oncogene amplification and its connection to cancer progression.
Premature chromosome condensation (PCC).
Fluorescence in situ hybridization (FISH).
Fluorescence microscopy for visualizing molecular and cellular components in cancer cells.
Scientific reporting and data presentation in the context of laboratory research.
Beurteilungskriterien
(*)A minimum 75% attendance is required. Students need to write a scientific report describing brief experiment procedures and results (1-2 pages). The positive assessment is "participated successfully", the negative assessment is "participated without success".
Lehrmethoden
(*)Introduction and supervision of experimental skills in medical teaching laboratory
