(*) Leider ist diese Information in Deutsch nicht verfügbar.
Workload
Ausbildungslevel
Studienfachbereich
VerantwortlicheR
Semesterstunden
Anbietende Uni
2 ECTS
R - Doktorat / PhD
Humanmedizin
Yong Yu
2 SSt
Johannes Kepler Universität Linz
Detailinformationen
Anmeldevoraussetzungen
Zulassung zum Doktoratsstudium Medical Sciences
Quellcurriculum
Doktoratsstudium Medical Sciences 2025W
Lernergebnisse
Kompetenzen
(*)Students understand the epigenetic mechanisms underlying X chromosome inactivation and Barr body formation. They can apply immunofluorescence (IF) and RNA-FISH techniques to detect key molecular markers and analyze the results.
Fertigkeiten
Kenntnisse
(*)
Identifying and explaining epigenetic regulatory mechanisms involved in X chromosome inactivation.
Performing immunofluorescence (IF) staining to detect histone modifications.
Conducting RNA-FISH staining to visualize long non-coding RNA (lncRNA) XIST.
Preparing slides for fluorescence microscopy and analyzing results.
Applying experimental techniques in molecular biology to study gene regulation.
(*)
Epigenetic regulation of X chromosome inactivation.
The role of long non-coding RNA XIST in gene silencing.
Mechanisms of histone modification in chromatin regulation.
Principles and applications of immunofluorescence (IF) staining.
RNA fluorescence in situ hybridization (RNA-FISH).
Beurteilungskriterien
(*)A minimum 75% attendance is required. Students need to write a scientific report describing brief experiment procedures and results (1-2 pages). The positive assessment is "participated successfully", the negative assessment is "participated without success".
Lehrmethoden
(*)Introduction and supervision of experimental skills in medical teaching laboratory
