| More specifically, upon completion of the course they will be able to
- carry out fundamental synthesis procedures following reported literature procedures (k3, k6)
- evaluate the basic safety relevant aspects of organic synthesis procedures (k5)
- carry out standard lab procedures to purify and isolate organic molecules such as crystallizations, distillations, column chromatography (k3, k4)
- characterize and analyze small organic molecules by spectroscopic means, i.e. NMR spectroscopy (k3, k4, k5)
- document their laboratory work in protocol books (k4)
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The course is divided into five consecutive sections devoted to the following experimental manipulations and reaction types:
- preparative separation of organic compounds based on their acid/base properties and characterization by physical properties (Melting point, boiling point, refractive index and simple IR, MS and NMR spectra)
- nucleophilic aliphatic substitution reactions
- reactions of carbonyl compounds
- electrophilic addition, elimination, reduction and oxidation reactions
- reactions of aromatic compounds
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