| Lehrinhalte |
(*)Medical applications for the design of antimicrobial and antibiotic drugs.
The course is comprised of individual topics designed to enhance recently covered topic in the area of modern medicinal biochemistry, including the development of antibiotics and antivirals as powerful tools against infectious agents. Acquired and inherited mechanisms of illnesses in humans at molecular level will be addressed, particularly in regards to energy metabolism (catabolic/anabolic pathways) as well as signalling cascades. The course provides a broad array of advanced knowledge in medicinal biochemistry and chemistry.
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| Sonstige Informationen |
(*)Oral Examination
Recommended reading:
E. De Clercq: Antiviral drugs in current clinical use. J. Clin. Virol. 30: 115-133, 2007. E. De Clercq: Status presens of antiviral drugs and strategies: part I, DNA viruses and retroviruses; part II, RNA viruses (except retroviruses). Adv. Antiviral Drug Design, vol. 5, in press (2007). E. De Clercq & A. Holy: Acyclic nucleoside phosphonates: a key class of antiviral drugs. Nature Rev. Drug Discovery 4: 928-940, 2005.
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