[ 875BIN1SAPV12 ] VL Sequence Analysis and Phylogenetics

Es ist eine neuere Version 2015W dieser LV im Curriculum Bachelor's programme Computer Science 2014S vorhanden.
Workload Education level Study areas Responsible person Hours per week Coordinating university
3 ECTS M1 - Master's programme 1. year Computer Science Sepp Hochreiter 2 hpw Johannes Kepler University Linz
Detailed information
Original study plan Master's programme Bioinformatics 2013W
Objectives Bioinformatics is an interdisciplinary field at the interface of life sciences and computational sciences that deals with the development and application of methods for storing, retrieving, and, in particular, analyzing biological data. The massive data amounts produced by recent and currently emerging high-throughput biotechnologies provide unprecedented potentials, but also pose yet unseen computational challenges – making bioinformatics an essential success factor for the advancement of fields, such as, molecular biology, genetics, medicine, and pharmacology.

This course focuses on basic methods for comparing biological sequences, such as, DNA, RNA, and amino acid sequences. This is complemented by an introduction to the field of phylogenetics, which is concerned with identifying evolutionary relationships among groups of organisms. No prior knowledge in biology is required for this course. Basics of molecular biology are provided up to the minimum that is necessary to understand the ideas behind the bioinformatics tools and algorithms discussed in this lecture.

  • Basics of molecular biology
  • Simple sequence comparisons and scoring schemes
  • Pairwise sequence alignment
  • Statistical analysis of sequence alignments
  • Multiple sequence alignment
  • Methods for computing evolutionary distance
  • Methods for computing phylogenetic trees
Criteria for evaluation Written exam
Methods Slide presentations complemented by examples presented on the blackboard
Language English
Study material Electronic course material is made available for download
Changing subject? No
Corresponding lecture in collaboration with 875BIN1ASPU12: UE Sequence Analysis and Phylogenetics (3 ECTS)
equivalent to

BIMPFKVBIN1: KV Bioinformatik I: Sequenzanalyse und Phylogenie (6 ECTS)
On-site course
Maximum number of participants -
Assignment procedure Direct assignment