Upon completing the course, students will possess the following skills.
They are able to
- describe the structural and mechanical properties of biological systems at different scales and assess the relevance of these properties for biological functions (k2, k3);
- explain the relationship between the structures of biological systems and their mechanical properties (k2);
- apply fundamental physical concepts to biological structures and processes and describe these structures and processes (k3);
- evaluate the suitability and limitations of experimental physical methods for studying biological systems (k3);
- apply learned physical principles to new or related biological questions (k4).
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During the course, students will acquire knowledge in the following areas and concepts of mechanobiology and tissue engineering:
- biopolymers;
- thermodynamics and kinetics of molecular interactions;
- effect of forces on molecular interactions;
- protein mechanics;
- viscoelasticity;
- cytoskeleton;
- molecular motors;
- cell mechanics;
- cell adhesion and migration;
- force generation and mechanosensing in biological systems;
- mechanical properties of tissues;
- mechanical regulation processes in mammalian, plant and bacterial cells.
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