(*)The following skills will be provided:
• Students can describe the basis of NMR for isolated spins, such as populations, energy levels, rotations of spin and magnetization vectors using classical physics concepts (k1,k2).
• Students can describe the NMR phenomenon for spin-1/2 nuclei (1H, 13C, 15N, 31P) in quantum mechanical (QM) terms, including populations, coherences, superposition states, single quantum and multiple quantum transitions (k1,k2).
• Students are able to use the vector representation to explain simple NMR experiments like pulses and precession (k3).
• Students are able to use the PrOF to analyze basic pulse sequence blocks like the spin echo and polarization transfer (k4).
• Students understand the principles behind many popular 2D NMR techniques used in organic chemistry and can decide on a suitable experiment for a given question about molecular structure (k2,k5).
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(*)• Quantum Mechanics: Wave functions, Hamiltonians, Operators, Product Operators, Transformations, Basis Sets, Expectation Values, Density Matrix, Hilbert Space, Liouville Space, Schrödinger Equation, Liouville-van Neumann equation
• Complex numbers, linear algebra, vectors, rotations, matrix algebra, eigenfunctions, eigenvalues
• Weak coupling, strong coupling
• RF pulse sequences
• Homonuclear 2D: COSY, TOCSY
• Polarization transfer techniques: INEPT, DEPT
• Heteronuclear 2D: HMQC, HSQC, HMBC
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