Inhalt

[ 863ABIUUAM24 ] Module The 'unknown unknowns' of arthropod-microbes interactions

Versionsauswahl
Workload Mode of examination Education level Study areas Responsible person Coordinating university
2 ECTS Accumulative module examination M1 - Master's programme 1. year (*)Biologische Chemie Jan Sterba USB Budweis
Detailed information
Original study plan Master's programme Biological Chemistry 2024W
Objectives The aims of the course are: (1) To provide a theoretical basis to understand the scope of arthropod-microbes interactions in nature. (2) To motivate students to explore the contribution of microbes in the biological systems they study. (3) To provide practical tools so they can design experiments including microbiome analysis and carry amplicon sequence analysis.
Subject 1. The journey of the microbe (Dr. Alejandro Cabezas-Cruz - INRAE, France) 2. Forces shaping the arthropod microbiome (Dr. Alejandra Wu-Chuang - INRAE, France) 3. The role of host-microbe cross-talk in regulating arthropod innate immunity (Dr. Ryan Rego - Institute of Parasitology, Czech Republic) 4. Vector-pathogen-microbiome interactions (Dr. Alejandro Cabezas-Cruz - INRAE, France) 5. Introduction to microbiome analysis (Dr. Dasiel Obregón Alvarez - University of Guelph, Canada) 6. Introduction to microbiome analysis using artificial intelligence (Dr. Fabien Vorimore - ANSES, France) 7. Introduction to network analysis (Prof. Agustín Estrada-Pe?a - University of Zaragoza, Spain) 8. Trans-kingdom molecular communication (Dr. Alejandro Cabezas-Cruz - INRAE, France) 9. Ecosystem Holobiont: importance of arthropod-microbes integration for the ecosystem (Dr. Micaela Tosi - University of Guelph, Canada) 10. Host-microbe interactions through evolutionary time (Dr. Kim Hoang - University of Oxford, UK)

Practical lesson 1: 16S rRNA amplicon sequence analysis Practical lesson 2: Data analysis based on Artificial Intelligence

Further information Criteria for valuation Exam in form of evaluated short manuscript-style report from the data analysis

Methods Monologic (reading, lecture, briefing), Dialogic (discussion, interview, brainstorming), Written action (comprehensive tests, clauses), Work with multi-media resources (texts, internet, IT technologies), Case studies

Study Material 'Gina Garland et al. A closer look at the functions behind ecosystem multifunctionality: A review. ', 'Yong-Xin Liu et al. A practical guide to amplicon and metagenomic analysis of microbiome data. ', 'Ziyuan Jiang et al. Accurate diagnosis of atopic dermatitis by combining transcriptome and microbiota data with supervised machine learning. ', 'Girish Neelakanta et al. Anaplasma phagocytophilum induces Ixodes scapularis ticks to express an antifreeze glycoprotein gene that enhances their survival in the cold. ', 'Constanza Schapheer, Roseli Pellens and Rosa Scherson. Arthropod-Microbiota Integration: Its Importance for Ecosystem Conservation. ', 'Alexis A. Smith et al. Cross-Species Interferon Signaling Boosts Microbicidal Activity within the Tick Vector. ', 'Benjamin J Callahan et al. DADA 2 : high-resolution sample inference from Iillumina amplicon data. ', 'Congmin Zhu et al. Determine independent gut microbiotadiseases association by eliminating the effects of human lifestyle factors Handouts, presentations

Subordinated subjects, modules and lectures