[ 663BCELBPH18 ] Module Biopharmacy

Workload Mode of examination Education level Study areas Responsible person Coordinating university
3 ECTS Accumulative module examination B2 - Bachelor's programme 2. year (*)Biologische Chemie Eva Benesova USB Budweis
Detailed information
Original study plan Bachelor's programme Biological Chemistry 2023W
Objectives The objective of this course is to give basic overview of current trends in biopharmaceuticals. The focus will be on 3 aspects of this broad theme: a) the use of living cell as a production apparatus b) on physiology principles of current biotechnology drugs c) practical examples of current biopharmaceuticals.

The course Biological drugs is focused on the field of pharmaceuticals which are produced by biotechnology approaches with the use of genetically modified both prokaryotic and eukaryotic organisms. In the opening parts, students will gain the basic information on the way of production of these biological drugs together with a basic information on related regulatory affairs. The course will then analyze differences between biological drugs

To give students basic information on this field of biological pharmaceuticals which represent currently most dynamic developing filed of pharmaceuticals. To give overview of current drugs, their structure, production and biological effects

The diversity of viruses exceeds that of all other living organisms, combined. This course will introduce students to virus genome organization and composition, transmission cycles, and mechanisms of infection and replication, as well as strategies to prevent or treat virus infections.

Subject The main concepts of biological pharmaceutics
Further information 1. Introduction: What is bio-pharmacy, history of biotechnology, current trends. 2. General steps in drug development: Pre-clinical and clinical phases, regulatory principles, costs of development. 3. Bio-macromolecules: A structural and functional view. 4. Analysis of bio-macromolecules - Analytical techniques used for determination of purity of biopharmaceuticals. 5. Differences between procaryotic and eucaryotic cells - Important differences for production of drugs. 6. Isolation of products - Major techniques of industrial isolation of bio-macromolecules. 7. Major drugs - hormones and cytokines 8. Major drugs - enzymes 9. Major drugs - vaccines 10. Major drugs - antibodies 11. Gene therapies 12. Safety of drugs and development of generic biopharmaceuticals. 13. Commercial aspects of this field. 14. Future directions and few comments on ethical issues.
Corresponding lecture ANTBICEBIPV10: VO Biopharmacy (3 ECTS) (as lecture)
Subordinated subjects, modules and lectures