Inhalt
[ 663MOBIITGV13 ] VL Introduction to Genetics
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| Workload |
Education level |
Study areas |
Responsible person |
Hours per week |
Coordinating university |
| 1,5 ECTS |
B1 - Bachelor's programme 1. year |
(*)Biologische Chemie |
Michael Breitenbach |
1 hpw |
Johannes Kepler University Linz |
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| Detailed information |
| Original study plan |
Bachelor's programme Biological Chemistry 2019W |
| Objectives |
Introducing basic concepts of genetics from a chemist's perspective
Preparation for the genetics and molecular biology classes in year 2
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| Subject |
Part I: Foundations of genetics, structure of DNA, Replication, Coding function of DNA
Part II: The genetic code, translation, co-linearity of gene and protein, tRNA, protein structure an folding, postsynthetic modifications, enzyme catalysis
Part III: Gene technology, plasmids, cloning vectors, DNA cloning and amplification, DNA sequencing, polymerase chain reaction, clone banks, cDNA cloning, genomic cloning, screening of clone banks, prokaryotic gene regulation: the lac-operon
Part IV: Genome structure, chromatin structure, chromosomes and nuclear domains, the genome remains constant in development, nuclear cloning, eukaryotic gene expression, trancriptomics, proteomics, the mitotic and meiotic cell cycle, life cycles of eukaryotes, recombination, crossing over, genetic mapping
Part V: Applications of Mendel’s laws, meiotic tetrads and the 2:2 segregation, the back cross, two factor crosses, application of mathematical probability theory, sex-linked inheritance, the human Y chromosome, mitochondrial inheritance, pedigree analysis, prenatal diagnosis, tests for heterozygosity, glossary of genetic terms
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| Criteria for evaluation |
Written Exam
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| Methods |
Lecture
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| Language |
English |
| Study material |
- Griffiths et al. An Introduction to genetic analysis, Freeman, NY, 2000
- Lodish et al. Molecular cell biology, Freeman, NY, 2016
- Alberts et al. Molecular biology of the cell, Garland, NY, 2015
- And the corresponding newer editions of all three books
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| Changing subject? |
No |
| Corresponding lecture |
663MOBIITGV13: VL Introduction to Genetics (1.5 ECTS)
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| On-site course |
| Maximum number of participants |
- |
| Assignment procedure |
Direct assignment |
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