The goal of the course is to provide an overview concerning opinions about origin of life, formation of first replicators on RNA basis, about origin and evolution of genetic code. Students will get familiar with present state of knowledge of genome structure and evolution, main mechanisms of genome formation, where especially genome dynamics will be stressed. Evolution of sexuality will be presented as well. Students will get a complex picture of strategies and methods of current genomics as well as its history.
Subject
1. Origin of life 2. Relics of RNA world and first genomes 3. Small RNAs, RNA interference (RNAi) 4. Evolution of genomes 5. Polyploidization 6. Evolution of genes 7. Genome dynamics I 8. Genome dynamics II 9. Evolution of sexual reproduction 10. Consequences of sexual reproduction 11. Structure and evolution of human genome 12. Genomics – methods and strategies 13. History of genomics
